Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord
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منابع مشابه
Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord
The notochord develops from notochord progenitor cells (NPCs) and functions as a major signaling center to regulate trunk and tail development. NPCs are initially specified in the node by Wnt and Nodal signals at the gastrula stage. However, the underlying mechanism that maintains the NPCs throughout embryogenesis to contribute to the posterior extension of the notochord remains unclear. Here, ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.08.003